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FACULTY Department Members By Category Laboratories Faculty Robert Salata, MD Chief Donald Anthony, MD, PhD Keith Armitage, MD Eric Arts, PhD David Bobak, MD Robert Bonomo, MD W. Henry Boom, MD David Canaday, MD Michael Cho, PhD Curtis Donskey, MD Scott Fulton, MD Yong Gao, MD, PhD Barbara Gripshover, MD Marion Helfand, MD Christina Hirsch, MD Marta Jakubowycz, MD Wei Jiang, MD John L Johnson, MD Michael Lederman, MD Tracy Lemonovich, MD Michelle Lisgaris, MD Amy Ray, MD Louis Rice, MD Benigno, Rodriguez, MD Roxana Rojas, MD Scott Sieg, PhD Richard Silver, MD Usha Stiefel, MD Zahra Toossi, MD Gopal Yadavalli, MD Research Staff Administrative Staff SEARCH: RELATED SITES:	Michael Lederman, MD Scott R Inkley Professor of Medicine Director ACTU/ CFAR Principal Investigator, CWRU/UHC AIDS Clinical Trials Unit Phone: (216) 844-8796 Fax: (216) 844-5523 E-mail: lederman.michael@clevelandactu.org Education MD- Mount Sinai School of Medicine, 1974 Residency- University Hospitals of Cleveland, 1978 Fellowship- Case Western Reserve University, 1980 Laboratory Research Dr. Lederman has served as intern, resident, chief resident in Medicine and fellow in Infectious Diseases at Case Western Reserve University where he joined the faculty in 1980. He is a member of the American Association of Immunologists, the Infectious Diseases Society of America, the HIV Medicine Association and is a councilor of the Clinical Immunology Society. He is on the editorial boards of AIDS, the Journal of AIDS and Clinical Immunology. NIH Biosketch Selected References: Lederman MM, Veazey R, Hartley O, Mosier D, Dufour J, Mefford M, Piatak M Jr. Salkowitz JR, Rodriguez B, Blauvelt A, Offord R. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 306:485-7, 2004. [PubMed] Salkowitz JR, Sieg SF, Harding CV, Lederman MM. In vitro human memory CD8 T cell expansion in response to cytomegalovirus requires CD4+ T cell help. J Inf Dis 204:971-83, 2004. [PubMed] Lange CG, Lederman MM, Medvik K, et al. Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection. Aids. Sep 26 2003;17(14):2015-2023. [PubMed] Quinones-Mateu ME, Lederman MM, Feng Z, et al. Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication. Aids. Nov 7 2003;17(16):F39-48. [PubMed] Sieg SF, Bazdar DA, Lederman MM. Impaired TCR-mediated induction of Ki67 by naive CD4+ T cells is only occasionally corrected by exogenous IL-2 in HIV-1 infection. J Immunol. Nov 15 2003;171(10):5208-5214. [PubMed]


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