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case western reserve university

DIVISION OF INFECTIOUS DISEASES AND HIV MEDICINE

 
 

John L Johnson, MD, FACP

Dowd

Professor of Medicine and International Health

 

Phone: (216) 844-2646
Fax: (216) 844-1632
E-mail: jlj@case.edu

Education

MD - University of Pittsburgh, 1981

Residency- Vanderbilt University Medical Center, 1985

Pulmonary/Critical Care Medicine – Case Western Reserve University/University Hospitals of Cleveland, 1987

Research

Dr. Johnson’s major research focus is phase I, II, and III IND and non-IND clinical trials of new drugs, immunotherapeutic agents and vaccines for the prevention and treatment of tuberculosis. Other areas of interest include HIV and TB interactions, immunopathogenesis of tuberculosis and M. avium complex disease, TB diagnostics, surrogate markers of response to TB treatment, pulmonary infections in immunocompromised persons, HIV vaccines and research capacity strengthening in developing countries. Dr. Johnson is the component leader for clinical trials for the NIH-sponsored Tuberculosis Research Unit at CWRU and the Principal Investigator for TB clinical trials for Site 30 - Kampala, Uganda of the CDC-sponsored Tuberculosis Trials Consortium (TBTC) network. Dr. Johnson works closely with international collaborators in Uganda, Brazil and the Philippines.

NIH Biosketch

 

Selected Publications

• Johnson JL, Ssekasanvu E, Okwera A, Mayanja H, Hirsch CS, Nakibali J, Drzayich Jankus D, Eisenach KD, Boom WH, Ellner JJ, Mugerwa RD for the Uganda-Case Western Reserve University Research Collaboration. Randomized trial of adjunctive interleukin-2 in adults with pulmonary tuberculosis. Am J Respir Crit Care Med 2003; 168:185-191.

• Wallis RS, Vinhas SA, Johnson JL, Ribeiro FC, Palaci M, Peres RL, Sá RT, Dietze R, Chiunda A, Eisenach K, Ellner JJ. Whole blood bactericidal activity during treatment of pulmonary tuberculosis. J Infect Dis 2003;187:270-278.

• Ribeiro-Rodrigues R, Co TR, Johnson JL, Ribeiro F, Palaci M, Sá RT, Maciel EL, Lima FEP, Dettoni V, Toossi Z, Boom WH, Dietze R, Ellner JJ, Hirsch CS. Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance. Clin Diagn Lab Immunol 2002;9: 818-823.

• Johnson JL, Okwera A. Hom DL, Mayanja H, Kityo C, Nsubuga P, Nakibali JG, Loughlin AM, Mugyenyi PN, Vernon A, Mugerwa RD, Ellner JJ, Whalen CC for the Uganda-Case Western Reserve University Research Collaboration. Duration of efficacy of treatment of latent tuberculosis infection in HIV-infected adults. AIDS 2001;15 (16):2137-2147.